Ovarian cancer treatment often consists of a combination of cytoreductive surgery and chemotherapy. The purpose of surgical treatment is to remove the tumour as well as any nearby tissues where cancer has spread. However, ovarian cancer frequently includes micrometastases that have spread from the ovaries to other parts of the body, in addition to a localised tumour. Surgery cannot treat micrometastatic cancer cells because it is a local treatment. As a result, either before or after cytoreductive surgery, also known as debulking surgery, a systemic treatment such as chemotherapy, which involves the use of powerful drugs that can enter the bloodstream to reach and destroy widespread cancer cells, may be used. An exploratory laparotomy, also known as upfront cytoreductive surgery, is the most common type of cytoreductive surgery used to treat ovarian cancer. A gynecologic oncologist can accurately diagnose and stage a tumour (the extent of tumour spread) during a laparotomy, remove as much cancer as possible from the abdominal and pelvic regions, and determine whether additional therapy is required.
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